However, larger studies with longer follow up are required before a wider application of this technique. It helps in maximizing DS and could offer an alternative to PD and aspiration thrombectomy in total occlusion. At 30 days, the major adverse cardiac event (MACE) rate was significantly lower in the DS group (2.4% versus 9.3%, P = 0.02), mainly driven by lower rates of target lesion revascularization (TLR) (0.9% versus 4.2%, P = 0.01).Ĭonclusion: This cost-effective technique appears to be simple, feasible and safe and is associated with superior clinical outcomes. The procedural complications were also significantly lower in DS group (0.6% versus 7.6%, P 50% after percutaneous coronary intervention (PCI) were significantly higher in the DS group (85.7% versus 71.1%, P < 0.001). Final TIMI 3 flow was achieved more frequently in the DS group as compared to PD group (96.7% versus 92.3%, P = 0.04). DBDS technique to facilitate DS was successful in 68% patients (211/309). Results: DS was done in 74% (n = 336) of the patients and 26% (n = 118) patients received stenting after pre-dilatation (PD). Patients with complete occlusion of the vessel after wire placement were subjected to deflated balloon-facilitated DS technique (DBDS technique) and DS was done wherever possible. DS was performed when the culprit vessel was visualized with at least TIMI flow grade 1. From September 2016 to June 2018, 454 patients were enrolled in the study. Methods: This was a prospective, observational, single-center pilot study. The aim of this study was to evaluate the feasibility, safety and outcomes of this novel technique in patients with STEMI in real-world clinical practice. We used deflated balloon to facilitate DS in patients with totally occluded culprit arteries. But in most cases, the thrombolysis in myocardial infarction (TIMI) flow remains ≤ 1 after wire placement. © 2008 Steinkopff Verlag Darmstadt.Background: Several studies and meta-analyses have shown that direct stenting (DS) may improve clinical outcomes in patients with acute ST-elevation myocardial infarction (STEMI). Conclusion: Post-interventional TIMI flow? 2 is strongly associated with adverse out-come during hospitalization and after 6 months following hospitalization. After 6 months, patients without restored normal TIMI flow had worse New York Heart Association functional class (NYHA), and had to undergo repeat coronary angiography more often. A regressions analysis showed that predictors leading to such flow patterns are diabetes (P = 0.013), pre-hospital fibrinolytic therapy (P = 0.017), cardiogenic shock (P = 0.002) and a 3-vessel disease (P = 0.003). In patients with post-interventional TIMI flow? 2 the left anterior descending coronary artery (LAD) was significantly more often seen as the target vessel (54.3% Vs. 11.4% P = 0.045) compared to patients with TIMI flow? 2.
24.3% P = 0.002) and use of intra-aortic balloon pump were all more unlikely (5.8% Vs. 44.2% P < 0.0001), and prehospital fibrinolytic therapy (6.3% Vs. 32.9% P < 0.0001), left ventricular ejection fraction was better (51.3 Vs. In this group, in-hospital mortality was significant lower (6.4% Vs. In 430 patients, post-interventional TIMI flow 3 could be established. Methods and results: Between 20, 500 patients underwent primary PCI for STEMI.
We retrospectively evaluated data from our single center "real world patients" database of patients undergoing primary PCI to determine differences in clinical and angiographic patterns in patients with or without restoring thrombolysis in myocardial infarction (TIMI) flow 3. Background: Growing evidence suggests that poor coronary blood flow after primary percutaneous coronary intervention (PCI) is associated with unfavorable clinical out-come.
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